Careers

Location- Yavne

Job description

Metabomed, a clinical stage cancer drug-discovery biotech company is looking for a Research assistant for cancer cell biology.

The position is for a hands-on research assistant for mammalian tissue culture work and requires an experienced MSc in life science. The ideal candidate would have a vast experience in tissue culture and cell biology techniques. He/she will take part in conducting biological experiments as part of an effort to discover and develop new cancer therapeutics.

Some of the specific areas of research include: validating potential cancer targets, establishing stable cell-lines, developing and performing biochemical and cell-based assays to support drug discovery efforts.

Contribute to the effective operation of the lab by sharing the responsibilities of preparing buffers and reagents, ordering supplies and maintaining equipment.

Minimum Requirements:

• MSc in cell biology with a minimum of 2 years’ experience
• The candidate must be experienced in mammalian cell culture and cell biology techniques, including transfection protocols, stable cells selection, Western blotting and qPCR.
• Candidate must be able to design and troubleshoot assays and experiments independently

Advantage

• Previous experience in a pharmaceutical or biotech companies
• Experience in cell-free biochemical assays
• Experience in multiple gene transfer protocols (transfection, lentivirus and adenovirus infection), somatic gene silencing (RNAi) and ablation (CRISPR/Cas9) as well as experience in cells production and immortalization from primary tissues

Protein Chemistry Scientist with Cell Biology experience

Metabomed, a promising startup in Merck incubator center, seeks an enthusiastic, experienced Protein Chemistry Scientist with Cell Biology experience to join our R&D team in Yavne.  This individual will be expected to develop and employ proteomics approaches to support target identification / deconvolution, target engagement, and mode-of-action (MOA) elucidation efforts in several drug discovery programs.

SKILLS AND EXPERIENCE

Ph.D. in Biochemistry, Cell-biology, or related discipline with relevant experience.

Experience with chemical-affinity enrichment to selectively enrich proteins and chemical biology techniques using probes (covalent and/or photoaffinity).

Experiences with Stable isotope labeling with amino acids (SILAC) or other quantitative proteomics techniques is an advantage.

Experience in isolating protein from complex biological samples and sample processing workflow for LC-MS analysis.

Experience in conducting, analyzing and interpreting LC-MS/MS proteomics data is an advantage.